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Research Interests(Full Synopsis)

Research in the McCarroll Group involves the application of analytical chemistry to solve complex chemical problems with an emphasis in the area of molecular spectroscopy. Current investigations include systems involving molecular and chiral recognition. We also have an interest in the development of fluorescent sensors and pseudostationary phases for use in micellar capillary electrophoresis (MCE). The primary techniques used in our laboratory include steady-state and time-resolved (ps) fluorescence spectroscopy, capillary electrophoresis and fluorescence polarization.

Selected Publications

"Characterization of Chiral Interactions using Fluorescence Anisotropy" Irene W. Kimaru, Yafei Xu, and Matthew McCarroll, Anal. Chem., 2006, accepted.

“Modulating Fluorescence Resonance Energy Transfer in Conjugated Liposomes”, Xuelian Li, Matthew McCarroll, and Punit Kohli, Langmuir, 2006, accepted.

"Chiral Recognition and Behavior of [1,1'-Binaphthalene]-2,2'-diol in Aqueous Solution by Fluorescence Spectroscopy", Yafei Xu and Matthew E. McCarroll, J. Photochem. Photobiol. A: Chem., 2006, 178, 50-56.

“Evaluation of Chiral Recognition in Cyclodextrins using Fluorescence Anisotropy”, McCarroll, M. E., Irene Kimaru, and Yafei Xu, Abderrazzak Douhal, Ed., Elsevier: Oxford, 2006 (in production) [invited contribution]

"Fluorescence Anisotropy as a Method to Examine Thermodynamics of Enantioselectivity", Yafei Xu and Matthew E. McCarroll, J. Phys. Chem. B, 2005, 109, 8144-8152.[PDF]

"Determination of Enantiomeric Composition by Fluorescence Anisotropy", Yafei Xu and Matthew E. McCarroll, J. Phys. Chem. A, 2004, 108, 6929-6932.[PDF]

"Fluorescence Anisotropy as a Measure of Chiral Recognition", Matthew E. McCarroll, Feresteh Haddadian, and Isiah M. Warner, J. Am. Chem. Soc., 2001, 123(13); 3173-3174.[PDF]