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GRADUATE COURSE DESCRIPTIONS
Dept. of Chemistry and Biochemistry
Southern Illinois University at Carbondale
411-3 Intermediate Inorganic Chemistry.
Fundamentals of inorganic chemistry, covering bonding and structure, coordination compounds and the chemistry of some familiar and less familiar elements. Three lectures per week. Prerequisite: 456 or 462 or concurrent enrollment. Offered spring semester only.
431-3 Environmental Chemistry.
Chemical principles applied to the environment and environmental problems. Chemical kinetic, thermodynamic and equilibrium concepts as they relate to the atmosphere, water and soil will be discussed to include current problems of pollutants, pollutant evaluation and pollutant remediation. Discussion of methods for the chemical analysis of environmental samples will also be included. Prerequisite: C or better in 230 and 340. Offered spring semester in even years only.
434-2 or 4 Instrumental Analytical Chemistry.
Theory and practice of instrumental measurements, including emission and absorption spectroscopic, capillary electrophoretic and chromatographic methods. Two lectures and two three-hour laboratories per week for four credits. Enrollment for two credit hours is restricted to graduate students in the Department of Chemistry and Biochemistry who are advised to take instrumental analysis. Laboratory fee: $30. Prerequisite: C or better 230. Offered fall semester only.
439-3 Forensic Chemistry.
A one-semester course covering the collection, handling and analyses of forensic samples and evidence. Topics include procedures to collect, preserve, maintain custody, analyze, validate the data and report conclusions from the analyses of crime related samples. Analytical methods for the qualitative and quantitative analyses of samples by gas chromatography, mass spectroscopy, infrared spectroscopy, fluorescence spectroscopy, ultraviolet and visible spectroscopy will be covered. Other techniques such as capillary and gel electrophoresis, high-pressure liquid chromatography, thin layer chromatography, blood splattering analyses, fingerprint identification, scanning electron microscopy and light microscopy may be included as time permits. One lecture and two three-hour periods containing laboratory experiments, demonstrations, and group discussions per week. Enrollment is limited with preference given to students with high academic standings. Laboratory fee: $30. Prerequisite: C or better in 230 and previous or concurrent enrollment in 434 and instructor consent. Offered spring semester only.
444-3 Intermediate Organic Chemistry.
A transitional course between introductory and graduate level chemistry. The chemistry of carbon compounds based upon a mechanistic approach will be discussed. Three lectures per week. Prerequisite: C or better in 340, 342. Offered fall semester in even years only.
451-6 (3, 3) Biochemistry.
(Same as Microbiology 451, Biochemistry 451 and Molecular Biology, Microbiology and Biochemistry 451)
(a) Chemistry and function of amino acids, proteins and enzymes; enzyme kinetics; chemistry, function and metabolism of carbohydrates; citric acid cycle; electron transport and oxidative phosphorylation.
(b) Chemistry, function and metabolism of lipids; nitrogen metabolism; nucleic acid and protein biosynthesis; metabolic regulation. Three lectures per week. Must be taken in a,b sequence. Prerequisite: one year of organic chemistry.
456-3 Biophysical Chemistry.
(Same as Biochemistry 456 and Molecular Biology, Microbiology and Biochemistry 456) A one-semester course in biophysical chemistry intended for biochemists and molecular biologists. Emphasis will be on solution thermodynamics, kinetics and spectroscopy applied to biological systems. Prerequisite: 340 and 342, 451a or concurrent enrollment, Mathematics 141 or 150.
461-3 Quantum Mechanics and Spectroscopy.
An introduction to quantum mechanics and spectroscopy. Prerequisite: Mathematics 250; C or better in 230, 342, 343; Mathematics 221 or 305 is recommended as prerequisite or concurrent enrollment.
462-3 Classical Physical Chemistry
An introduction to chemical, statistical thermodynamics and kinetics. Prerequisite: Mathematics 250; C or better in 230, 342, 343; Mathematics 221 or 305 is recommended as prerequisite or concurrent enrollment. Offered spring semester only.
466-2 (1,1) Physical Chemistry Laboratory.
A two-semester laboratory sequence. One three-hour laboratory per week per semester. (a) Experiments relating to topics covered in 462 Prerequisite: 462 or 456 or concurrent enrollment. (b) Experiments relating to topics covered in 461. Laboratory fee: $30. Prerequisite: 461 or concurrent enrollment. 466a offered spring semester only. 466b offered fall semester only.
468-3 Application of Symmetry to Chemistry
The concepts of symmetry elements, groups and character tables will be taught. Symmetry will be applied to molecules in order to simplify and characterize their wave functions and vibrational frequencies. Prerequisite: C or better in 461 or consent of instructor. Offered spring semester in odd years only.
479-3 Principles of Materials Chemistry.
Introduction to fundamental concepts of materials chemistry. Synthesis, characterization, processing and applications of different materials including solids, polymers, ceramics and molecularly designed materials. Prerequisite: 411, 462 or concurrent enrollment, or consent of instructor. Offered fall semester in odd years only.
489-1 to 3 Special Topics in Chemistry. Prerequisite: consent of instructor and of chair.
511-6 (3,3) Advanced Inorganic Chemistry.
(a)Principles of group theory and their application to molecular structure, ligand field theory and its application and magnetic properties of matter.
(b) Energetics, kinetics and mechanisms of inorganic systems. Prerequisite: one year of physical chemistry, 411.
519-1 to 9 (1 to 3 per semester) Advanced Topics in Inorganic Chemistry.
Metal ions in biological processes and other selected topics to be announced by the department. Maximum credit nine semester hours. Prerequisite: consent of instructor.
531-3 Introduction to Analytical Separations.
An introduction to the basic principles underlying separation science, with emphasis on all major chromatographies, gel and capillary electrophoresis, isoelectric focusing, field-flow fractionation, rate and isopynic sedimentation, filtration, reverse osmosis and related methods. Prerequisite: Mathematics 250.
532-3 Analytical Chemistry Instrumentation.
Introduction to analog and digital electronics and the computer control of system components. The course will focus on chemical instrumental and the use of filters, amplifiers and digital signal processing to improve sensitivity and detection limits. Two lectures and one three-hour laboratory per week. Prerequisite: 434.
533-3 Analytical Spectroscopy.
Fundamental and experimental aspects of electronic and vibrational spectrometry, with a particular emphasis on the spectroscopic analysis of atomic and molecular species. Various sources of electromagnetic radiation, detectors, optical components and the optimization of experimental methods are covered in detail. Common spectroscopic techniques are covered in detail and a portion of the course covers newly emerging techniques and developments. Prerequisite: 434.
534-3 Electrochemistry.
Fundamentals and applications of electrochemical methods, with emphasis on the thermodynamics and kinetics of electron transfer, electrode double-layer structures, as well as varied voltammetric techniques. Prerequisite: 462.
535-3 Advanced Analytical Chemistry.
Course surveys various statistical, data-manipulative, and numerical methods as applied to analytical chemistry, including probability distributions, methods of maximum likelihood, linear and nonlinear least squares, correlation coefficients, chi-square, F and T distributions, Pearson statistics, analysis of variance, convolution, deconvolution, cross-correlation, autocorrelation, data acquisition, Nyquist theorem, aliasing, digitization errors, digital filtering, Monte Carlo methods, and finite-difference equations. Prerequisite: 434.
536-3 Principles of Mass Spectrometry.
This course is an introduction to mass spectrometry with a focus on pharmaceutical and biological applications. Topics that will be covered include instrument design, ionization techniques, tandem mass spectrometry, chromatography/mass spectrometry and mass spectral interpretation. Prerequisite: 434.
537-3 Fluorescence Spectroscopy.
Fundamental and experimental aspects of analytical methods based on the various phenomena of luminescence. General principles of luminescence are covered in detail, as well as analytical techniques based on fluorescence quenching, energy transfer, polarization, and time resolved methods. Aspects of source of electromagnetic radiation, detectors, and electronic/optical components are discussed specifically as they pertain to fluorescence spectroscopy. Newly emerging fluorescence based techniques are also discussed. Prerequisite: 434 and 533 (or consent of the instructor).
539-1 to 9 (1 to 3 per semester) Advanced Topics in Analytical Chemistry.
Selected topics of interest to practicing analytical chemists such as microanalytical chemistry, functional-group chemical determinations, absorption spec-troscopy and electroanalytical chemistry. Maximum credit nine semester hours. Prerequisite: 434.
541-3 Organic Structure and Reactivity.
Structure and reactivity of organic compounds: steric, electronic, kinetic and thermodynamic aspects and their relation to reactive intermediates. Prerequisite: Master’s degree in chemistry, or a grade of B or better in 444, or passing grade on the organic diagnostic examination.
542-3 Mechanistic Organic Chemistry.
Reaction mechanisms in organic chemistry. Electrocyclic and sigmatropic reactions, cycloadditions, free radicals, photochemistry and organometallic catalysis. Spectroscopic methods. Prerequisite: Master’s degree in chemistry, or a grade of B or better in 444, or passing grade or the organic placement examination.
Orbital symmetry, photochemistry and the chemistry of the common transient intermediates. Prerequisite: Master’s degree in chemistry, or a grade of B or better in 444, or passing grade on the organic placement examination.
543-3 Synthetic Organic Chemistry.
Organic synthesis: classical and modern methods. Prerequisite: Master’s degree in chemistry, or a grade of B or better in 444, or passing grade on the organic chemistry placement examination.
549-1 to 9 (1 to 3 per semester) Advanced Topics in Organic Chemistry.
Specialized topics in organic chemistry. The topic to be covered is announced by the department. Maximum credit nine semester hours. Prerequisite: 542.
560-3 Introduction to Quantum Chemistry.
Basic principles and applications of quantum mechanics to chemistry. Topics include operator and vector algebra, classical mechanics, angular momentum, approximate methods, hydrogen-like atoms and molecular electronic structure. Three lectures per week. Prerequisite: one year of un-dergraduate physical chemistry.
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